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Correction: Kang et al. Fluid Flow to Electricity: Capturing Flow-Induced Vibrations with Micro-Electromechanical-System-Based Piezoelectric Energy Harvester. <i>Micromachines</i> 2024, <i>15</i>, 581.

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Robotic Cell Rotation Based on Optimal Poking Direction.

Chunlin Zhao1,2, Yaowei Liu3,4, Mingzhu Sun5,6

  • 1Institute of Robotics and Automatic Information System (IRAIS), Nankai University, Jinnan District, Tianjin 300350, China. zhaocl@mail.nankai.edu.cn.

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Summary
This summary is machine-generated.

This study introduces a robotic cell rotation strategy using an optimal poking direction for precise 3D cell manipulation. This method enhances efficiency and success rates in biological applications like oocyte rotation.

Keywords:
high efficiencyoptimal poking directionrobotic cell rotationslip-resistance

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Area of Science:

  • Biotechnology
  • Robotics
  • Cell Biology

Background:

  • Manual cell manipulation lacks repeatability and efficiency.
  • Robotic methods using micropipettes exist but lack optimal parameters.
  • Precise 3D cell orientation is crucial for biological manipulation.

Purpose of the Study:

  • To develop a robotic cell rotation strategy based on optimal poking direction.
  • To enhance the efficiency and success rate of cell manipulation.
  • To address limitations of current manual and robotic cell manipulation techniques.

Main Methods:

  • Analysis of forces applied to cells to determine optimal poking direction for maximum moment of force.
  • Design of micropipette movement trajectories for controlled rotational force application.
  • Application of the strategy to oocyte rotation in nuclear transfer procedures.

Main Results:

  • The robotic strategy achieved an average completion time of 23.6 seconds.
  • A success rate of 93.3% was recorded at a micropipette speed of 100 μm/s.
  • The method effectively overcame slippage, demonstrating high efficiency.

Conclusions:

  • The proposed optimal poking direction strategy significantly improves robotic cell rotation.
  • This technique offers a highly efficient and repeatable solution for 3D cell manipulation.
  • The method shows promise for applications such as nuclear transfer and other delicate biological procedures.