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Tongue Pressure Sensing Array Integrated with a System-on-Chip Embedded in a Mandibular Advancement Splint.

Yun-Ting Chen1, Kun-Ying Yeh2, Szu-Han Chen3

  • 1Department of Mechanical Engineering, National Taiwan University, Taipei 10617, Taiwan. ytchen@mems.me.ntu.edu.tw.

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Summary

A novel pressure sensing array in a mandibular advancement splint (MAS) accurately measures tongue pressure to assess obstructive sleep apnea (OSA) treatment effectiveness. This wearable device offers a sensitive, reliable method for monitoring OSA therapy outcomes.

Keywords:
conductive polymermandibular advancement splintobstructive sleep apneapressure sensing arraysystem-on-chip

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Area of Science:

  • Biomedical Engineering
  • Medical Devices
  • Sleep Medicine

Background:

  • Obstructive sleep apnea (OSA) is a prevalent condition characterized by upper airway obstructions during sleep.
  • Mandibular advancement splints (MAS) are oral appliances used as a potential treatment for OSA.
  • Accurate monitoring of MAS efficacy in treating OSA requires detailed physiological measurements.

Purpose of the Study:

  • To develop and evaluate a highly-sensitive pressure sensing array integrated into a MAS.
  • To measure tongue pressure distribution for determining the effectiveness of MAS in OSA treatment.
  • To create a wearable system-on-chip (SoC) device for sleep monitoring and data analysis.

Main Methods:

  • Fabrication of a flexible sensing array using an interdigital electrode pair and conductive polymer films.
  • Integration of the sensing array with an SoC for data retrieval, storage, and transmission.
  • Patterning conductive polymer films with microdomed structures to enhance sensitivity and reduce response time.

Main Results:

  • The developed pressure sensing array demonstrated high sensitivity and a reduced response time.
  • Negligible crosstalk effect was observed between individual sensing elements.
  • The sensing array maintained minimal sensitivity changes after prolonged water submersion (100 h), indicating robustness.

Conclusions:

  • The integrated MAS with a pressure sensing array and SoC is a promising tool for monitoring OSA treatment.
  • The device enables objective assessment of tongue pressure, crucial for evaluating MAS efficacy.
  • The system offers a sensitive, reliable, and durable solution for sleep monitoring in OSA patients.