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Related Experiment Video

Updated: Feb 2, 2026

Author Spotlight: Developing Innovative Therapeutic Strategies for Hemorrhagic Shock Research
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PREDICTORS OF FATAL OUTCOME IN PATIENTS WITH HEMORRHAGIC SHOCK IN GASTROINTESTINAL BLEEDING.

A O Girsh, A M Stukanov, S V Chernenko

    Vestnik Khirurgii Imeni I. I. Grekova
    |November 15, 2018
    PubMed
    Summary

    Key indicators of fatal outcomes in severe hemorrhagic shock patients include decreased body temperature, blood pH, and ionized calcium levels. Elevated lactate and prolonged activated partial thromboplastin time also correlate with mortality in hospital treatment.

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    Area of Science:

    • Medical research
    • Clinical diagnostics
    • Emergency medicine

    Background:

    • Hemorrhagic shock, particularly degree III, presents significant mortality risks.
    • Identifying reliable clinical and laboratory markers is crucial for predicting patient outcomes.

    Purpose of the Study:

    • To identify statistically reliable clinical and laboratory markers associated with fatal outcomes in patients with degree III hemorrhagic shock during hospital treatment.

    Main Methods:

    • Retrospective analysis of clinical and laboratory data from patients with degree III hemorrhagic shock.
    • Statistical correlation analysis to identify markers linked to mortality.

    Main Results:

    • A decrease in body temperature (below 35.9°C) is associated with fatal outcomes.
    • Lower pH of venous blood (below 7.19) and reduced ionized calcium (below 0.32 mmol/L) correlate with mortality.
    • Increased lactate levels (above 4.1 mmol/L) and elevated activated partial thromboplastin time (above 59 seconds) are linked to fatal outcomes.

    Conclusions:

    • Specific laboratory values and physiological parameters serve as reliable predictors of mortality in severe hemorrhagic shock.
    • Monitoring temperature, blood pH, ionized calcium, lactate, and aPTT can aid in risk stratification and management of these critical patients.