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Related Experiment Video

Updated: Feb 2, 2026

A Porcine Corneal Endothelial Organ Culture Model Using Split Corneal Buttons

A Porcine Corneal Endothelial Organ Culture Model Using Split Corneal Buttons

Published on: October 6, 2019

Flap Melting Over Corneal Inlay for Hyperopic Correction.

Suphi Taneri, Saskia Kiessler, Anika Rost

Journal of Refractive Surgery (Thorofare, N.J. : 1995)

|November 15, 2018

Summary

Corneal inlays used for hyperopic correction can cause severe flap melting and vision loss years after implantation. Prompt explantation can restore visual acuity, highlighting potential biocompatibility concerns.

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Engineered Vascularized Muscle Flap

Engineered Vascularized Muscle Flap

Published on: January 11, 2016

Area of Science:

Ophthalmology
Biomaterials Science
Corneal Surgery

Background:

Corneal inlays are implanted to correct refractive errors.
LASIK flaps are used to create a pocket for inlay insertion.

Observation:

Two patients developed flap melting and corneal opacification years after inlay implantation for hyperopic correction.
This complication led to a sudden loss of corrected distance visual acuity (CDVA).

Findings:

Flap melting occurred 9 and 11 years postoperatively in the two patients.
Explantation of the corneal inlays resulted in the recovery of CDVA to 1.0 in both cases.

Implications:

Corneal inlays may present delayed biocompatibility issues.
Long-term monitoring is essential for patients with corneal inlays.
Surgical intervention may be required to manage inlay-related complications.