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Published on: September 12, 2014
[The American opioid overdose crisis: A threat for France?]
D Vodovar1, J Langrand2, N Tournier3
1Centre antipoison et de toxicovigilance de Paris, hôpital Fernand-Widal, 200, rue du Faubourg-Saint-Denis, 75010 Paris, France; Fédération de toxicologie FeTox, hôpital Lariboisière/Fernand-Widal, AP-HP, 75010 Paris, France; Inserm UMRS 1144, 4, avenue de l'Observatoire, 75006 Paris, France; Service hospitalier Fréderic Joliot/CEA, laboratoire IMIV, boulevard Dubreuil, 91400 Orsay, France; Université Paris-Diderot, 75013 Paris, France.
Abstract:
Since the 2000s, a concerning increase in opioid-analgesic-related overdoses and deaths has been reported in the United States. In contrast with opioid overdoses reported in the 80-90s mostly involving heroin, currently it is the misuse of opioid analgesics that is mainly responsible for opioid overdoses. This crisis is related to factors (not limited to the US) which occurred during the 90s and which have led to a broad prescription of opioids in non-cancer pain. In Europe and France, there is (but to a much lesser extent) an increase in strong opioid consumption and in opioid prescription related morbi-mortality. This situation, which can be described as "worrying" today, requires awareness among the French medical community, both upstream (rational prescription of opioids) and downstream (optimal management of opioid poisoning) from the opioid prescription.
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