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Updated: Feb 2, 2026

Isolation, Culture, and Characterization of Primary Dermal Fibroblasts from Human Keloid Tissue
Published on: July 28, 2023
Keloid negatively affects body image.
Thamy Harumi Cardoso Motoki1, Felipe Contoli Isoldi1, Maria José de Azevedo Brito1
1Universidade Federal de São Paulo (UNIFESP/EPM) - Plastic Surgery Division, São Paulo, Brazil.
Keloid scars, a human-exclusive skin condition, can negatively impact body image. This study found that 40% of keloid patients experienced body image disturbances, affecting their self-esteem.
Area of Science:
- Dermatology
- Psychology
- Plastic Surgery
Background:
- Keloid is a unique human cicatricial neoplasm with unclear physiopathogenesis.
- The disfiguring nature of keloids can significantly impact a patient's body image perception.
- Understanding this impact is crucial for comprehensive patient care.
Purpose of the Study:
- To evaluate the psychological impact of keloids on patients' body image.
- To assess the correlation between keloid presence and body dysmorphic symptoms.
- To investigate the effect of keloids on self-esteem.
Main Methods:
- A cohort of 61 patients with keloids on socially visible body areas was studied.
- Participants underwent clinical evaluation, including anamnesis and physical examination.
- Standardized questionnaires, the Body Dysmorphic Symptoms Scale (BDSS) and Rosenberg Self-Esteem Scale, were administered.
Main Results:
- Forty percent of patients reported negative body image aspects, indicated by a BDSS score of 6 or higher.
- Patients with negative body image perceptions showed significantly lower self-esteem.
- An average Rosenberg Scale score of 10.5 was observed in affected patients (p<0.03).
Conclusions:
- The presence of keloids demonstrably has a negative effect on an individual's body image.
- Keloid scarring is associated with psychological distress and diminished self-worth.
- Further research into managing the body image disturbances caused by keloids is warranted.
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