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Updated: Feb 2, 2026

Functional Assessment of BRCA1 variants using CRISPR-Mediated Base Editors
Published on: February 28, 2021
More Is More: Semiannual Breast MRI Screening in BRCA1 Mutation Carriers
Christiane K Kuhl1, Simone Schrading2
1Department of Diagnostic and Interventional Radiology, RWTH Aachen University, Aachen, Germany. ckuhl@ukaachen.de.
Abstract:
Although annual MRI screening has improved early diagnosis of hereditary breast cancer, fast growth rates of BRCA1-associated cancers can still lead to interval cancers and/or node-positive disease. Using MRI with shorter screening intervals helps to effectively avoid both interval cancers and node-positive stages, whereas there is no role for mammography in these women.See related article by Guindalini et al., p. 1786.
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