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Omalizumab improves forced expiratory volume in 1 second in patients with severe asthma
Krzysztof Pałgan1, Magdalena Żbikowska-Götz1, Kinga Lis1
1Department of Allergy, Clinical Immunology and Internal Medicine, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.
Introduction:
Asthma is a multiphenotypic disease, and therapeutic managenment in patients with severe asthma is particulary difficult, with conventional treatment of severe asthma showing poor efficacy.
Aim:
To analyse forced expiratory volume in 1 s (FEV1) following the adminstration of omalizumab.
Material And Methods:
Six patinents (mean age: 50 ±12.6) with severe, uncontrolled asthma according to the GINA guidelines were enrolled in the study.
Results:
Treatment with omalizumab increased in all subjects FEV1 by 17.28 ±13.4% after months and 18.57 ±13.4% after 12 months of treatment.
Conclusions:
These results provides further evidence that therapy with omalizumab improves spiromtric parameters in severe asthma.
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