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Updated: Feb 2, 2026

Murine Fetal Echocardiography

Murine Fetal Echocardiography

Published on: February 15, 2013

Early fetal echocardiography.

Angela McBrien^1,2, Lisa K Hornberger^1,2,3

¹Fetal & Neonatal Cardiology Program, Division of Cardiology, Department of Pediatrics, Stollery Children's Hospital, Edmonton, Alberta, Canada.

Birth Defects Research

|November 16, 2018

Summary

Early fetal echocardiography is a reliable tool for detecting congenital heart disease in early pregnancy. While it has limitations, it offers valuable insights into fetal cardiac development and potential issues.

Keywords:

congenital heart disease fetal echocardiography first trimester

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Murine Fetal Echocardiography

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Published on: February 15, 2013

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Area of Science:

Perinatology
Fetal Cardiology
Medical Imaging

Background:

Congenital heart disease (CHD) is a significant concern in fetal development.
Early identification of fetal cardiac anomalies is crucial for timely intervention.
Advances in ultrasound technology enable earlier fetal cardiac assessments.

Purpose of the Study:

To evaluate the technical aspects and clinical utility of early fetal echocardiography.
To document cardiac structure and function differences in the late first/early second trimester.
To review the literature on early fetal echocardiography indications, safety, and accuracy.

Main Methods:

Review of existing literature on early fetal echocardiography.
Analysis of personal experiences with late first/early second trimester fetal echocardiography.
Exploration of clinical indications, technical aspects, safety, and accuracy.

Main Results:

Early fetal echocardiography reliably detects a high proportion of CHD in experienced hands.
Limitations include assessment of pulmonary veins, atrioventricular valves, and later-developing lesions.
Hemodynamic differences exist between early and later pregnancy assessments.

Conclusions:

Early fetal echocardiography is an established tool for CHD detection in utero.
It provides insights into the spectrum and progression of CHD.
Awareness of safety, technical aspects, and differing hemodynamics is essential.