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Updated: Feb 2, 2026

Mechanical Ventilation Boot Camp Curriculum
Published on: March 12, 2018
Rescue therapy for hypercapnia due to high PEEP mechanical ventilation in patients with ARDS and renal failure
April A Grant1,2, Valerie J Hart1,2, Edward B Lineen1,2
1Dewitt Daughtry Family Department of Surgery, Division of Trauma, University of Miami, Leonard M. Miller School of Medicine, Miami, Florida.
Abstract:
Extracorporeal removal of carbon dioxide in patients experiencing severe hypercapnia due to lung protective mechanical ventilation was first described over four decades ago. There have been many devices developed and described in the interim, many of which require additional training, resources, and staff. This manuscript describes a readily available and relatively simple adjunct that can provide partial lung support in patients with acute respiratory distress syndrome complicated by severe hypercapnia and acute kidney injury requiring dialysis.
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