Related Experiment Video
Updated: Aug 13, 2026

Experimental and Imaging Techniques for Examining Fibrin Clot Structures in Normal and Diseased States
Published on: April 1, 2015
Altered blood rheology in the pathogenesis of diabetic and other neuropathies
1Pathology Department, University of Otago Medical School, Dunedin, New Zealand.
Abstract:
Although a substantial literature confirms the abnormal flow properties of diabetic blood, only in a few papers has the vasculitis of diabetic neuropathy been considered to have a hemorheological cause. It is proposed that the pathogenesis of nerve lesions involves an interaction between the specialized nerve vascular system and focal ischemic lesions resulting from rheologically induced stasis. The proposition is extended into other conditions with abnormal blood rheology such as hypothyroidism, uremia, dysglobulinemia, polyarteritis nodosa, and lepromatous leprosy. It is concluded that the treatment of such polyneuropathies should include an agent which would improve the flow properties of the blood.
More Related Videos
Related Concept Videos
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
Type II Diabetes II: Pathophysiology
Diabetic Foot Ulcer
Diabetic Retinopathy
Diabetic Nephropathy
Diabetic Neuropathy

