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Related Experiment Videos

Intrathoracic lymphadenopathy in postprimary tuberculosis.

J H Woodring1, H M Vandiviere, C Lee

  • 1Department of Diagnostic Radiology, Albert B. Chandler Medical Center, University of Kentucky, Lexington 40536-0084.

Southern Medical Journal
|August 1, 1988
PubMed
Summary

Hilar or mediastinal lymphadenopathy is not exclusive to primary tuberculosis. This finding challenges the long-held belief that its presence excludes reactivation tuberculosis in adults.

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Area of Science:

  • Pulmonology
  • Infectious Diseases
  • Radiology

Background:

  • Hilar or mediastinal lymphadenopathy was historically considered indicative of primary Mycobacterium tuberculosis infection.
  • Its presence was often used to exclude diagnoses of reactivation or postprimary tuberculosis.

Observation:

  • A study examined 56 adult patients diagnosed with postprimary tuberculosis.
  • Hilar or mediastinal lymphadenopathy was identified in 5% of these patients.

Findings:

  • Intrathoracic lymphadenopathy, while more frequent in primary tuberculosis, is not a definitive diagnostic criterion for it in adults.
  • The study suggests that the presence of hilar or mediastinal lymphadenopathy does not rule out postprimary tuberculosis.

Implications:

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  • Roentgenographic findings of intrathoracic lymphadenopathy should not be solely relied upon to diagnose primary tuberculosis in adults.
  • Clinical and research criteria for tuberculosis diagnosis may need re-evaluation to include lymphadenopathy in postprimary cases.