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[Pathogen spectrum of non-gonorrhea urethritis]
U Schmidt1, M Hartmann, H Pfützner
1Klinik und Poliklinik für Hautkrankheiten, Friedrich-Schiller-Universität Jena, DDR.
Zeitschrift Fur Urologie Und Nephrologie
|May 1, 1988
Summary
Chlamydia trachomatis is the primary cause of non-gonococcal urethritis (NGU) in 40% of cases. Other pathogens like Ureaplasma urealyticum and Trichomonas vaginalis also contribute to NGU, necessitating broad diagnostic and therapeutic considerations.
Area of Science:
- Urology
- Microbiology
- Infectious Diseases
Context:
- Non-gonococcal urethritis (NGU) is a common infection affecting males.
- Understanding the etiological spectrum of NGU is crucial for effective treatment.
- Previous studies have indicated various causative agents, but regional data is essential.
Purpose:
- To identify the primary causative agents of non-gonococcal urethritis (NGU) in the German Democratic Republic (GDR).
- To determine the prevalence of Chlamydia trachomatis, Ureaplasma urealyticum, Trichomonas vaginalis, and Candida albicans in NGU patients.
- To highlight the importance of considering the identified germ spectrum and sexual partners in NGU diagnosis and therapy.
Summary:
- Cultural investigations in 333 males with NGU and 158 controls revealed Chlamydia trachomatis as the main pathogen (40%).
- Ureaplasma urealyticum (≥10^4 germs/ml urine) caused 15% of chlamydia-negative NGU, and Trichomonas vaginalis caused 5%.
- Candida albicans was significantly more frequent in patients (21%) than controls (4%), with other bacteria causing NGU in isolated cases.
Impact:
- This study provides critical etiological data on NGU within the GDR, informing clinical practice.
- Highlights the need for comprehensive diagnostic approaches to cover a broad range of potential pathogens.
- Emphasizes the importance of partner notification and treatment in managing NGU effectively.