Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Super-resolution Fluorescence Microscopy01:37

Super-resolution Fluorescence Microscopy

14.5K
Super-resolution fluorescence microscopy (SRFM) provides a better resolution than conventional fluorescence microscopy by reducing the point spread function (PSF). PSF is the light intensity distribution from a point that causes it to appear blurred. Due to PSF, each fluorescing point appears bigger than its actual size, and it is the PSF interference of nearby fluorophores that causes the blurred image. Various approaches to achieving higher resolution through SRFM have recently been...
14.5K
Computed Tomography01:10

Computed Tomography

8.3K
Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
8.3K
Chromatographic Resolution01:15

Chromatographic Resolution

2.1K
In chromatography, a solute moves through a chromatographic column and tends to spread, forming a Gaussian-shaped band. The longer the solute spends in the column, the broader the band becomes. The broadening can lead to overlaps within the column, affecting separation effectiveness.
The effectiveness of separation can be evaluated by determining the level of separation between two neighboring peaks in a chromatogram, which represents the individual components of a sample.
In chromatography,...
2.1K
Positron Emission Tomography01:29

Positron Emission Tomography

7.2K
Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
7.2K
Racemic Mixtures and the Resolution of Enantiomers02:30

Racemic Mixtures and the Resolution of Enantiomers

21.8K
A racemic mixture, or racemate, is an equimolar mixture of enantiomers of a molecule that can be separated using their unique interaction with chiral molecules or media. Racemic mixtures are denoted by the (±)- prefix. This ‘optical rotation descriptor’ applies to the whole solution of a racemic mixture rather than a specific stereoisomer. Enantiomers typically have the same physical and chemical properties. Hence, they are not easily separable. However, enantiomers can exhibit...
21.8K
High-Resolution Mass Spectrometry (HRMS)01:15

High-Resolution Mass Spectrometry (HRMS)

2.5K
The resolution of a mass spectrometer depends on the efficiency of separating ions with different ion masses. The mass of an atom is approximated to the sum of the masses of protons and neutrons inside, considering the masses of protons and neutrons as equal. However, the masses of the proton (1.6726 × 10−24 g) and neutron (1.6749 × 10−24 g) are not truly equal. There is a minor error in the expression of atomic masses relative to the simplest atom of hydrogen. For...
2.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Synchronized UAV multi-angle inversion of canopy structure parameters in wheat breeding materials.

Plant phenomics (Washington, D.C.)·2026
Same author

SVM-Based Optical Detection of Retinal Ganglion Cell Apoptosis.

Photonics·2026
Same author

KnitLoRA: bridging low-rank adaptation as interwoven layers for deeper semantic reasoning.

Scientific reports·2026
Same author

Leveraging self-healing CASH gel for enhanced paracrine secretion of mesenchymal stem cells to boost endometrial regeneration.

Biomaterials·2026
Same author

Enhancing progressive ensemble learning via normalized extra-Gradient initialization.

Neural networks : the official journal of the International Neural Network Society·2026
Same author

Preoperative prediction of KRAS mutation in rectal cancer using a combined T2-weighted imaging radiomics and volumetric apparent diffusion coefficient histogram model.

Abdominal radiology (New York)·2026
Same journal

Analysis of End-Tidal CO2 Variability During Plateau Waves Episodes: An Information Theoretic Approach<sup></sup>.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025
Same journal

AI and Tomosynthesis for Breast Cancer Molecular Subtyping: A step toward precision medicine<sup></sup>.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025
Same journal

Towards Sustainable Protein Recovery from Biological Waste: Assessing Polyethersulfone-based Microfiltration.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025
Same journal

Analysis of the cardiovascular response to standardized polymicrobial peritonitis experimental model.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025
Same journal

Automated Wrist Ultrasound Image Bone Enhancement and Segmentation Using Deep Learning.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025
Same journal

A Deep Learning approach for Depressive Symptoms assessment in Parkinson's disease patients using facial videos.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025
See all related articles

Related Experiment Video

Updated: Feb 2, 2026

Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography
11:21

Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography

Published on: January 15, 2013

12.0K

Super-Resolution in Optical Coherence Tomography.

Qifan Wang, Rencheng Zheng, Alin Achim

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
    |November 17, 2018
    PubMed
    Summary
    This summary is machine-generated.

    This study enhances optical coherence tomography (OCT) image resolution using inverse problem solutions. The alternating direction method of multipliers (ADMM) with soft thresholding significantly improves OCT image quality for retinal disease diagnosis.

    More Related Videos

    Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
    06:15

    Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

    Published on: August 9, 2024

    1.9K
    Doppler Optical Coherence Tomography of Retinal Circulation
    10:46

    Doppler Optical Coherence Tomography of Retinal Circulation

    Published on: September 18, 2012

    19.3K

    Related Experiment Videos

    Last Updated: Feb 2, 2026

    Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography
    11:21

    Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography

    Published on: January 15, 2013

    12.0K
    Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
    06:15

    Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

    Published on: August 9, 2024

    1.9K
    Doppler Optical Coherence Tomography of Retinal Circulation
    10:46

    Doppler Optical Coherence Tomography of Retinal Circulation

    Published on: September 18, 2012

    19.3K

    Area of Science:

    • Medical Imaging
    • Computational Imaging
    • Ophthalmology

    Background:

    • Optical coherence tomography (OCT) is crucial for diagnosing retinal diseases.
    • Image degradation, particularly resolution issues, commonly affects OCT image quality.
    • Enhancing OCT image resolution is vital for accurate diagnosis.

    Purpose of the Study:

    • To address and improve the resolution of degraded OCT images.
    • To propose novel solutions for OCT image deconvolution and super-resolution.
    • To evaluate different regularization techniques and algorithms for OCT image enhancement.

    Main Methods:

    • Formulated a cost function for deconvolution and super-resolution.
    • Employed alternating direction method of multipliers (ADMM) and forward-backward splitting (FBS) algorithms.
    • Compared L1 norm regularization with soft thresholding against total variation (TV) and nonconvex regularization methods.
    • Developed methods for estimating the unknown point spread function (PSF) in OCT images.

    Main Results:

    • The ADMM scheme with L1 norm regularization and soft thresholding demonstrated superior performance in enhancing OCT image quality.
    • Both standard and nonconvex regularization approaches were evaluated on synthetic and real human eye OCT images.
    • The proposed methods successfully addressed resolution issues in OCT imaging.

    Conclusions:

    • The ADMM algorithm with soft thresholding is an effective method for improving OCT image quality.
    • Accurate PSF estimation is important for successful deconvolution in OCT imaging.
    • The developed techniques offer significant potential for advancing retinal disease diagnosis through improved OCT imaging.