Towards An Open-Source Framework For The Analysis Of Cerebrovasculature Structure

Area of Science:

• Neuroscience
• Biomedical Engineering
• Computational Biology

Background:

• Graph-based analysis is common for studying microcirculation and cerebrovascular networks.
• Existing methodologies for cerebrovascular structure analysis are often briefly described and not publicly available.

Purpose of the Study:

• To introduce the foundational elements of an open-source framework for analyzing cerebrovascular structure.
• To address the need for standardized and accessible methods in microcirculation research.

Main Methods:

• Development of foundational components for an open-source framework.
• Focus on streamlining the analysis of vascular filaments within image volumes.

Main Results:

• Laying the groundwork for a comprehensive and complete framework for cerebrovascular analysis.
• Establishing a basis for accessible and standardized microvessel analysis.

Conclusions:

• A standardized, open-source framework is essential for advancing microcirculation studies.
• The proposed framework will facilitate more efficient and reproducible analysis of cerebrovascular networks.