Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

System of Memory01:23

System of Memory

7.4K
Memory is categorized into three major systems: sensory memory, short-term memory (STM), and long-term memory (LTM). These systems differ in their capacity and the duration for which they can hold information. Sensory memory captures raw sensory input from the environment, holding it for just a few seconds or less. For example, on hearing a brief, loud sound, like a car horn honking, the sound seems to linger in the mind for a moment even after it stops. This is an instance of sensory memory...
7.4K
Working Memory01:24

Working Memory

883
Working memory refers to a combination of components, including short-term memory and attention, that allow an individual to hold information temporarily as we perform cognitive tasks. It is an essential cognitive function that enables the execution of complex tasks such as problem-solving, comprehension, and reasoning. Unlike short-term memory, which simply involves the storage of information for a brief period, working memory involves the active manipulation and processing of this...
883
Optimal Foraging00:48

Optimal Foraging

13.8K
How animals obtain and eat their food is called foraging behavior. Foraging can include searching for plants and hunting for prey and depends on the species and environment.
13.8K
Drug Distribution: Volume of Distribution01:25

Drug Distribution: Volume of Distribution

7.4K
The volume of distribution refers to the theoretical volume necessary to contain the entire amount of an administered drug at the same concentration observed in the blood plasma. The body's intracellular fluid compartment, which makes up two-thirds of the total body water, is contrasted with the extracellular fluid compartment—comprising plasma and interstitial fluid—that accounts for one-third. The volume of distribution can vary depending on the characteristics of the drug.
7.4K
Long-Term Memory01:18

Long-Term Memory

681
Long-term memory is a relatively permanent type of memory, capable of storing vast amounts of information over extended periods. Its storage capacity is generally considered unlimited.
Long-term memory can be categorized into two primary types: explicit and implicit memory. Explicit memory, also known as declarative memory, involves the conscious recollection of information that we deliberately try to remember, recall, and articulate. This type of memory encompasses specific facts, events, and...
681
Traumatic Memory01:20

Traumatic Memory

583
Emotionally traumatic events often lead to memories that are exceptionally vivid and enduring, sometimes persisting with remarkable clarity throughout an individual's life. A classic example of this phenomenon is a person who survives a car accident. Even years later, they may recall every detail of the event with startling accuracy — the screeching of the tires, the jarring impact, and the acrid smell of burning rubber. Such vividness contrasts sharply with how an individual...
583

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Corrigendum to "Revisiting subcallosal cingulate deep brain stimulation for depression: Long-term safety and effectiveness outcomes from a pooled analysis of 172 implanted patients" [Brain Stimul 18 (2025) 1632-1640].

Brain stimulation·2026
Same author

Exercise evokes retained motor performance without neuroprotection in a mouse model of Parkinson's disease.

Frontiers in physiology·2026
Same author

Developing a global framework to assess a country's readiness and resilience to introduce a new vaccine or improve uptake of an underutilized vaccine.

Expert review of vaccines·2026
Same author

Modeling the Public Health Impact of Improved Antiretroviral Therapy Restart Patterns Among People with HIV Who Have Discontinued Treatment.

Journal of health economics and outcomes research·2026
Same author

Magnetic resonance-guided focused ultrasound for the management of tremor: update on the position statement of the American Society for Stereotactic and Functional Neurosurgery.

Journal of neurosurgery·2026
Same author

Neuropsychological outcomes comparing traditional surgical approaches and laser interstitial therapy for refractory mesial temporal lobe epilepsy: A systematic review and meta-analysis.

Epilepsia·2026
Same journal

Analysis of End-Tidal CO2 Variability During Plateau Waves Episodes: An Information Theoretic Approach<sup></sup>.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025
Same journal

AI and Tomosynthesis for Breast Cancer Molecular Subtyping: A step toward precision medicine<sup></sup>.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025
Same journal

Towards Sustainable Protein Recovery from Biological Waste: Assessing Polyethersulfone-based Microfiltration.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025
Same journal

Analysis of the cardiovascular response to standardized polymicrobial peritonitis experimental model.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025
Same journal

Automated Wrist Ultrasound Image Bone Enhancement and Segmentation Using Deep Learning.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025
Same journal

A Deep Learning approach for Depressive Symptoms assessment in Parkinson's disease patients using facial videos.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025
See all related articles

Related Experiment Video

Updated: Feb 2, 2026

The Spatial Memory Game: Testing the Relationship Between Spatial Language, Object Knowledge, and Spatial Cognition
05:15

The Spatial Memory Game: Testing the Relationship Between Spatial Language, Object Knowledge, and Spatial Cognition

Published on: February 19, 2018

11.4K

Bayesian Optimization of Asynchronous Distributed Microelectrode Theta Stimulation and Spatial Memory.

Omer Ashmaig, Mark Connolly, Robert E Gross

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
    |November 17, 2018
    PubMed
    Summary
    This summary is machine-generated.

    This study optimized electrical brain stimulation for epilepsy, finding a balance between reducing seizures and preserving spatial memory. Bayesian optimization successfully tuned parameters to improve memory performance while managing therapeutic effects.

    More Related Videos

    Assessing Spatial Learning and Memory in Small Squamate Reptiles
    08:44

    Assessing Spatial Learning and Memory in Small Squamate Reptiles

    Published on: January 3, 2017

    8.0K
    Transcranial Direct Current Stimulation tDCS for Memory Enhancement
    10:37

    Transcranial Direct Current Stimulation tDCS for Memory Enhancement

    Published on: September 18, 2021

    15.7K

    Related Experiment Videos

    Last Updated: Feb 2, 2026

    The Spatial Memory Game: Testing the Relationship Between Spatial Language, Object Knowledge, and Spatial Cognition
    05:15

    The Spatial Memory Game: Testing the Relationship Between Spatial Language, Object Knowledge, and Spatial Cognition

    Published on: February 19, 2018

    11.4K
    Assessing Spatial Learning and Memory in Small Squamate Reptiles
    08:44

    Assessing Spatial Learning and Memory in Small Squamate Reptiles

    Published on: January 3, 2017

    8.0K
    Transcranial Direct Current Stimulation tDCS for Memory Enhancement
    10:37

    Transcranial Direct Current Stimulation tDCS for Memory Enhancement

    Published on: September 18, 2021

    15.7K

    Area of Science:

    • Neuroscience
    • Biomedical Engineering
    • Epilepsy Research

    Background:

    • Medication-resistant epilepsy requires novel treatments beyond drugs and surgery.
    • Electrical stimulation, like asynchronous distributed microelectrode stimulation (ADMETS), shows promise for seizure reduction.
    • ADMETS can negatively impact spatial memory, with effects dependent on stimulation amplitude.

    Purpose of the Study:

    • To develop a method for optimizing electrical stimulation parameters to maximize therapeutic efficacy while minimizing side effects.
    • To investigate the trade-offs between seizure reduction and spatial memory performance in epilepsy treatment.
    • To apply closed-loop Bayesian optimization for fine-tuning hippocampal stimulation.

    Main Methods:

    • Utilized a tetanus toxin rat model of mesial temporal lobe epilepsy.
    • Employed asynchronous distributed microelectrode stimulation (ADMETS) in the hippocampus.
    • Implemented closed-loop Bayesian optimization to tune stimulation parameters based on spatial memory performance.

    Main Results:

    • Demonstrated that ADMETS reduces seizure frequency in the epilepsy model.
    • Showed that ADMETS negatively impacts spatial memory, with the effect proportional to stimulation amplitude.
    • Successfully used Bayesian optimization to maximize spatial memory performance by tuning stimulation parameters.

    Conclusions:

    • Closed-loop Bayesian optimization offers a principled approach to optimize complex stimulation therapies.
    • This method can effectively balance therapeutic benefits (seizure reduction) with cognitive side effects (spatial memory).
    • Optimized hippocampal stimulation holds potential for treating medication-resistant epilepsy with improved cognitive outcomes.