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Inter-Limb Muscle Synergy of Hands-and-Knees Crawling in Typical Developing Infants and Infants with Developmental

Qi L Xiong, Xiao Y Wu, Jun Yao

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
    |November 17, 2018
    PubMed

    Insights

    Infants with confirmed developmental delay showed fewer muscle synergies during crawling, suggesting impaired neuromuscular control. This finding may aid early diagnosis of cerebral palsy in infants.

    Area of Science:

    • Neuroscience
    • Developmental Pediatrics
    • Biomechanics

    Background:

    • Inter-limb muscle coordination is crucial for infant motor development.
    • Crawling is a key milestone reflecting neuromuscular maturation.
    • Understanding muscle synergies in crawling can reveal developmental differences.

    Purpose of the Study:

    • To quantify and compare inter-limb muscle coordination during crawling.
    • To differentiate muscle synergy patterns between typically developing infants and those with developmental delay.
    • To explore the potential of muscle synergy metrics as biomarkers for early diagnosis.

    Main Methods:

    • Collected surface electromyography and kinematic data from infants crawling.
    • Analyzed eight arm and leg muscles and joint kinematics.
    • Used nonnegative matrix factorization to identify muscle synergies.

    Main Results:

    • No significant difference in muscle synergies between typically developing and at-risk infants.
    • Infants with confirmed developmental delay exhibited a reduced number of muscle synergies.
    • Constrained neuromuscular control was indicated in infants with developmental delay.

    Conclusions:

    • Reduced muscle synergies in crawling may underlie motor impairments in developmental delay.
    • Muscle synergy analysis shows promise as a biomarker for early cerebral palsy diagnosis.
    • This metric offers insights into neuromuscular strategies in infant development.

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