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Updated: Feb 2, 2026

Noninvasive Electrocardiography in the Perinatal Mouse
Published on: June 12, 2020
Influence of Wilson Ce nter Terminal on fetal electrocardiography acquisition
Abstract:
The acquisition of a standard 10-leads electrocardiography (ECG) is performed using the Wilson Center Terminal (WCT) reference with a normalized electrode positioning. However, in the case of non-invasive fetal ECG (fECG) acquisition, there is no standardization on the positioning of the electrodes on the abdomen and many authors suggest an acquisition with or without a WCT. The use of the WCT for the acquisition of the fetal heart rate (FHR) is not justified. The objective of this paper is to quantify the influence of this reference compared to a direct measurement. For this purpose, we developed a device allowing the acquisition of the fECG and compared the two configurations on 6 volunteer pregnants. The noise levels and the fetal QRS morphology were compared, showing no superiority of the WCT acquisition compared to a direct differential measurement.
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