Intracranial multiple myeloma with intraparenchymal involvement: Case report and literature review

Area of Science:

• Neurology
• Oncology
• Hematology

Background:

• Multiple myeloma is a hematologic malignancy characterized by plasma cell proliferation.
• Intraparenchymal involvement of the central nervous system by multiple myeloma is exceptionally rare.

Observation:

• This report describes a unique case of multiple myeloma with lesions adjacent to the meninges.
• The patient presented with intraparenchymal lesions within the brain tissue.

Findings:

• The findings highlight an unusual pattern of central nervous system (CNS) involvement in multiple myeloma.
• Demonstrates the potential for extramedullary disease manifestation in the brain parenchyma.

Implications:

• This case expands the understanding of the rare neurological complications of multiple myeloma.
• Highlights the importance of considering intraparenchymal myeloma in the differential diagnosis of CNS lesions in affected patients.