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Risk factors associated with postoperative prosthetic graft patency in Leriche syndrome

Miju Bae1, Sung Woon Chung1, Chung Won Lee1

  • 1Department of Thoracic and Cardiovascular Surgery, Pusan National University Hospital, Republic of Korea.

Asian Journal of Surgery
|November 17, 2018
PubMed

Insights

Graft thrombosis is a major challenge in Leriche syndrome surgery. Strict blood pressure control and improved distal artery flow are key for better prosthetic graft patency after repair.

Area of Science:

  • Vascular Surgery
  • Graft Patency Research
  • Aortoiliac Occlusive Disease Management

Background:

  • Postoperative graft thrombosis is a significant clinical challenge in Leriche syndrome.
  • Aortoiliac occlusive disease requires surgical intervention with prosthetic grafts.

Purpose of the Study:

  • To identify factors influencing prosthetic graft patency after surgical repair for Leriche syndrome.
  • To improve outcomes for patients undergoing aortoiliac reconstruction.

Main Methods:

  • Retrospective review of 51 patients undergoing surgery for aortoiliac occlusive disease (2007-2014).
  • Cox proportional hazard model used to analyze factors associated with graft patency.

Main Results:

  • The 2-year prosthetic graft patency rate was 72.5%.
  • Younger age, uncontrolled postoperative hypertension, and TASC II D femoropopliteal lesions were significantly associated with lower graft patency.
  • Comorbidities necessitating axillo-bifemoral bypass correlated with reduced patency or complications.

Conclusions:

  • Strict postoperative hypertension control is crucial for enhancing graft patency.
  • Addressing distal run-off issues is necessary for successful open surgical repair of Leriche syndrome.
  • Optimizing patient selection and perioperative management can improve long-term graft survival.
Abstract

Keywords:
Arterial occlusive diseaseGraft occlusionLeriche syndromeVascularVascular patency

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