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Utility of Anakinra in Acute Crystalline Diseases: A Retrospective Study Comparing a University Hospital with a
Julianna Desmarais1,2, Cong-Qiu Chu3,4
1From the Division of Arthritis and Rheumatic Diseases, Oregon Health & Science University; Rheumatology Section, Veterans Affairs (VA) Portland Health Care System, Portland, Oregon, USA. desmaraj@ohsu.edu.
Objective:
To evaluate the efficacy and safety of anakinra in inpatient management of acute gout and pseudogout.
Methods:
Hospitalized patients with acute gout (n = 77) or pseudogout (n = 11) or both (n = 3) were analyzed for response to anakinra and adverse effects.
Results:
Half of all patients had comorbidities limiting the treatment choice. Anakinra was well tolerated, and 92% of gout flares and 79% of pseudogout flares responded to treatment.
Conclusion:
Anakinra is an effective and safe treatment for acute gout and pseudogout in hospitalized patients, particularly in those with comorbidities.
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