Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Renal osteodystrophy.

J A Kanis, T F Cundy, N A Hamdy

    Bailliere'S Clinical Endocrinology and Metabolism
    |February 1, 1988
    PubMed
    Summary
    This summary is machine-generated.

    Advances in understanding renal osteodystrophy reveal calcitriol deficiency

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Efficacy of weekly teriparatide does not vary by baseline fracture probability calculated using FRAX.

    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2015
    Same author

    FRAX and the effect of teriparatide on vertebral and non-vertebral fracture.

    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2015
    Same author

    FRAX-based assessment and intervention thresholds--an exploration of thresholds in women aged 50 years and older in the UK.

    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2015
    Same author

    Effective secondary fracture prevention: implementation of a global benchmarking of clinical quality using the IOF Capture the Fracture® Best Practice Framework tool.

    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2015
    Same author

    Comparative performance of current definitions of sarcopenia against the prospective incidence of falls among community-dwelling seniors age 65 and older.

    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2015
    Same author

    Burden of high fracture probability worldwide: secular increases 2010-2040.

    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2015
    Same journal

    Phytoestrogen content in foods.

    Bailliere's clinical endocrinology and metabolism·1999
    Same journal

    Soyfoods, isoflavones and risk of colonic cancer: a review of the in vitro and in vivo data.

    Bailliere's clinical endocrinology and metabolism·1999
    Same journal

    Experimental studies on lignans and cancer.

    Bailliere's clinical endocrinology and metabolism·1999
    Same journal

    Reproductive actions of phytoestrogens.

    Bailliere's clinical endocrinology and metabolism·1999
    Same journal

    Phytoestrogens and inhibition of angiogenesis.

    Bailliere's clinical endocrinology and metabolism·1999
    Same journal

    Phytoestrogens and diseases of the prostate gland.

    Bailliere's clinical endocrinology and metabolism·1999
    See all related articles

    Area of Science:

    • Nephrology
    • Bone Metabolism
    • Mineral and Bone Disorders

    Background:

    • Significant progress in understanding renal osteodystrophy pathophysiology and treatment over the last decade.
    • Improved comprehension of calcitriol deficiency's role in early renal failure hyperparathyroidism.
    • Growing awareness of subtle aluminum effects on bone, despite less florid disease.

    Purpose of the Study:

    • To review recent advances in the understanding and treatment of renal osteodystrophy.
    • To highlight the ongoing challenges in managing hyperparathyroid bone disease in long-term dialysis patients.
    • To discuss the potential impact of early vitamin D intervention and evolving renal replacement therapies.

    Main Methods:

    • Review of current literature on renal osteodystrophy.

    Related Experiment Videos

  • Analysis of the pathophysiology of hyperparathyroidism and aluminum toxicity in chronic kidney disease.
  • Discussion of treatment strategies including vitamin D therapy and dialysis modalities.

    • Main Results:

    • Calcitriol deficiency is a key factor in hyperparathyroidism in early renal failure.
    • Subtle aluminum effects on bone are increasingly recognized.
    • Long-term management of hyperparathyroid bone disease remains a significant challenge.
    • Parathyroid gland proliferation on dialysis requires further investigation into cellular regulation.

    Conclusions:

    • Early intervention with vitamin D shows promise but long-term outcomes require further study.
    • Understanding cellular events in parathyroid hormone production and replication is crucial.
    • Evolving treatments for renal replacement therapy will continue to influence bone disease in kidney patients.