Related Experiment Video
Updated: Feb 2, 2026

Normothermic Cardiac Arrest and Cardiopulmonary Resuscitation: A Mouse Model of Ischemia-Reperfusion Injury
Published on: August 30, 2011
Double Sequence Defibrillation for Out-of-hospital Cardiac Arrest: Unlikely Survival
Andrew Zabel1, James R Bence2, Kyle Couperus3
1William Beaumont Army Medical Center, El Paso, Texas.
Abstract:
Survival from out-of-hospital cardiac arrest (OHCA) is highest with early defibrillation and immediate, high-quality cardiopulmonary resuscitation. Return of spontaneous circulation (ROSC) is rare in OHCA. The purpose of this discussion and case report is to highlight the use of double sequence defibrillation (DSD) for refractory ventricular fibrillation (RVF). We present a 58-year-old male with RVF who successfully achieved ROSC after 38 minutes using DSD and had a good neurological outcome. DSD has shown promise in many case reports and case series as a means of increasing ROSC and survival rates in OHCA.
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