Related Experiment Video
Updated: Feb 2, 2026

Isolation and Characterization of Mesenchymal Stromal Cells from Human Umbilical Cord and Fetal Placenta
Published on: April 3, 2017
Effect of Dentin Matrix Components on the Mineralization of Human Mesenchymal Stromal Cells
Xenos Petridis1, Bas P Beems1, Phillip L Tomson2
11Center for Dentistry and Oral Hygiene, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Impact Statement:
This research has been conducted with the aim to contribute to the development of treatment modalities for the reconstruction of lost/damaged mineralized tissues. Currently, determining the most appropriate stromal cell population and signaling cues stands at the core of developing effective treatments. We provide new insights into the effect of innate inductive cues found in human dentin matrix components, on the osteogenic differentiation of various human stromal cell types. The effects of dentin extracellular matrix components on umbilical cord mesenchymal stromal cells have not been investigated before. The findings of this study could underpin translational research based on the development of techniques for mineralized tissue engineering and will be of great interest for the readership of Tissue Engineering Part A.
Related Concept Videos
Water and Mineral Acquisition
Mesenchymal Stem Cells
Minerals
Major...
The Extracellular Matrix
Overview of Cell-Matrix Interactions
Components of Stress
Interestingly, the hidden cube faces also experience these stresses, equal and...

