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Novel and Innovative Hybrid Technique for Type A Aortic Dissection
Published on: March 28, 2025
Management of Patients With Coronary Artery Malperfusion Secondary to Type A Aortic Dissection
Maximilian Kreibich1, Joseph E Bavaria2, Emanuela Branchetti2
1Division of Cardiovascular Surgery, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania; Department of Cardiovascular Surgery, Heart Center Freiburg University, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Insights
Coronary artery malperfusion in type A aortic dissection requires tailored surgical repair. Coronary artery bypass grafting is recommended for severe lesions, while ostial repair is effective for less complex cases.
Area of Science:
- Cardiovascular Surgery
- Thoracic Surgery
- Aortic Dissection
Background:
- Coronary artery malperfusion is a serious complication of type A aortic dissection.
- Understanding the different types of coronary artery involvement is crucial for surgical planning.
Purpose of the Study:
- To review the surgical experience with coronary artery malperfusion secondary to type A aortic dissection.
- To evaluate the outcomes of different repair strategies for coronary artery malperfusion.
Main Methods:
- Retrospective review of 76 patients with coronary artery malperfusion between 2002 and 2017.
- Classification of lesions into type A (ostial flap), type B (coronary artery involvement), and type C (complete avulsion).
- Analysis of surgical repair success rates, need for coronary artery bypass grafting, and patient survival.
Main Results:
- Ostial repair was successful in 88% of type A and 63% of type B lesions.
- Coronary artery bypass grafting was necessary for all type C lesions and some type B lesions.
- Perioperative mortality was 24%, but survival rates were similar between patients with and without coronary artery malperfusion.
Conclusions:
- Coronary artery bypass grafting is recommended for type C lesions or those with underlying coronary artery disease.
- Ostial pledgetted suture repair is effective for type A and type B lesions when antegrade cardioplegia is feasible.
- Despite high perioperative mortality, long-term survival is not adversely affected by coronary artery malperfusion with appropriate management.
Background:
This study reviewed our experience with coronary artery (CA) malperfusion secondary to type A aortic dissection.
Methods:
Between 2002 and 2017, 76 patients presented with CA malperfusion, with a dissection flap limited to the aorta in the region of the coronary ostium (type A lesion) in 26 (34%), with a dissection flap involving the CA itself (type B lesion) in 32 (42%), or with complete avulsion of the CA (type C lesion) in 18 (24%).
Results:
Ostial repair was successfully performed in 23 type A patients (88%), in 20 type B patients (63%), and in no type C patient (0%). CA bypass grafting was performed when antegrade cardioplegia could not be applied in all 18 type C patients (100%) and in 5 type B patients (16%) because of a primary entry at the coronary ostium and in 7 patients (type A: 3 patients [12%], type B: 4 patients [13%]) with evidence of CA disease (p < 0.001). Perioperative mortality in patients with CA malperfusion was high (18 patients [24%]), but there was no difference in short-term (p = 0.153) or long-term survival (log-rank p = 0.542). Also, a landmark analysis showed equal survival of discharged patients with and without CA malperfusion (log-rank p = 0.645).
Conclusions:
We recommend CA bypass grafting in patients with type C lesions or in patients with underlying CA disease for optimal delivery of cardioplegia and ostial pledgetted suture repair in patients with type A lesions or type B lesions when the administration of antegrade cardioplegia is successful.
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