Susceptibility of orbiviruses to low pH and to organic solvents

Six orbiviruses, Corriparta, Wallal, Eubenangee, D'Aguilar, Warrego and Mitchell River, were inactivated within 30 min in solutions of pH less than 6. All but Wallal virus resisted treatment with ether at 1 degrees for 22 h but only Corriparta virus resisted treatment with chloroform at 1 degrees for 22 h. The genomes of the orbiviruses, including Corriparta virus, after electrophoresis in acrylamide gels separated into basically similar patterns which were distinct from the pattern of reovirus RNA.