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Measles in Italy: Viral strains and crossing borders
Fabio Magurano1, Melissa Baggieri1, Francesca Mazzilli1
1National Reference Laboratory for Measles and Rubella - Department of Infectious Diseases, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.
Abstract:
In 2017, Italy experienced one of the largest outbreaks of measles in recent years, with 5404 notified cases and 4347 confirmed cases. A further 2029 cases were notified during the first 6 months of 2018, and 1516 of them were laboratory-confirmed. The B3 and D8 genotypes were identified as those responsible for the outbreak. Possible transmission routes can be established by monitoring the circulating measles virus strains in support of the national health authorities to warn people and travellers.
Insights
Italy faced a significant measles outbreak in 2017-2018, with genotypes B3 and D8 identified. Monitoring virus strains helps public health officials track transmission routes and alert the public and travelers.
Area of Science:
- Epidemiology
- Virology
- Public Health
Background:
- Italy reported a major measles outbreak in 2017 with over 5,400 cases.
- The outbreak continued into 2018, with over 2,000 notified cases in the first six months.
Purpose of the Study:
- To identify the specific measles virus genotypes responsible for the 2017-2018 Italian outbreak.
- To understand potential transmission routes for public health interventions.
Main Methods:
- Analysis of notified and confirmed measles cases in Italy.
- Laboratory confirmation and genotyping of measles virus strains.
Main Results:
- Genotypes B3 and D8 were identified as the primary strains circulating during the outbreak.
- A substantial number of measles cases were confirmed through laboratory testing.
Conclusions:
- Genotype surveillance is crucial for understanding measles transmission dynamics.
- Monitoring circulating strains aids national health authorities in issuing timely warnings to the public and travelers.
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