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Flavonoids: biological activities and therapeutic potential.
Mércia Marques Jucá1, Francisco Mauricio Sales Cysne Filho1, Jamily Cunha de Almeida2
1Department of Physiology and Pharmacology, Faculty of Medicine, Federal University of Ceará, Fortaleza, Brazil.
Flavonoids, plant-derived phenolic compounds, exhibit diverse biological activities like antioxidant effects. This review details their groups, mechanisms, and confirmed health benefits, highlighting their therapeutic potential.
Area of Science:
- Biochemistry
- Pharmacology
- Nutraceuticals
Background:
- Flavonoids are a diverse class of plant phenolic compounds.
- They exhibit significant in vitro biological activities, including antioxidant effects and enzyme modulation.
- Their therapeutic potential is of great research interest.
Purpose of the Study:
- To review key aspects of flavonoids.
- To describe known flavonoid groups and their mechanisms of action.
- To consolidate information on their pharmacological properties and health benefits.
Main Methods:
- Systematic review of scientific literature.
- Searches conducted across major databases: Scopus, Science Direct, PubMed, SciVerse, and SciELO.
- No time restriction applied to the search.
Main Results:
- Flavonoids possess a wide range of biological activities.
- Previous studies have confirmed pharmacological properties and health benefits of specific flavonoids.
- Understanding their mechanisms and effects is crucial for therapeutic applications.
Conclusions:
- Flavonoids represent a promising area for therapeutic development.
- Further research can elucidate their full health benefits and applications.
- This review provides a comprehensive overview for researchers and practitioners.
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