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Author Spotlight: Development and Evaluation of a Compound Acne Rodent Model Using C. acnes and Oleic Acid
Published on: November 1, 2024
Four new compounds from Dendrobium devonianum
Leilei Wu1, Ye Lu1, Yulian Ding1
1a The Ministry of Education Key Laboratory for Standardization of Chinese Medicines, The State Administration of Traditional Chinese Medicine Key Laboratory for New Resources and Quality Evaluation of Chinese Medicines , Institute of Chinese Materia Medica of Shanghai University of Traditional Chinese Medicine, Shanghai R&D Center for Standardization of Chinese Medicines , Shanghai , P.R. China.
Abstract:
Two new phenanthrenes dendrodevonin A and B, two new aliphatic acids dendrodevonic acid A and B, along with ten known compounds, were isolated from the stems of Dendrobium devonianum. The structures of new compounds were elucidated on the basis of MS and NMR spectroscopic data, and single-crystal X-ray diffraction analysis. The cytotoxicities of isolates towards HT-29 cell were discussed, and 4-methoxy-2,7-phenanthrenediol exhibited inhibitory activity compared with other studied compounds.
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