Recent Advances in Pediatric Concussion and Mild Traumatic Brain Injury

Andrea Ana Almeida1, Matthew Thomas Lorincz1, Andrew Nobuhide Hashikawa2

  • 1Department of Neurology, Michigan Medicine, Michigan NeuroSport, 2301 Commonwealth Boulevard, Suite 1022, Ann Arbor, MI 48105, USA.

Insights

Pediatric concussions are a growing public health issue. A multidisciplinary approach can help reduce recovery time for children with head injuries.

Area of Science:

  • Pediatric medicine
  • Neurology
  • Public health

Background:

  • Concussions in children represent a significant public health concern.
  • Primary care physicians increasingly manage pediatric concussions.
  • Diagnosis relies on clinical assessment, despite available ancillary tests.

Purpose of the Study:

  • To highlight the challenges in diagnosing and managing pediatric concussions.
  • To emphasize the benefits of a multidisciplinary approach.
  • To address the controversy surrounding sport retirement in pediatric concussion cases.

Main Methods:

  • Clinical diagnosis remains primary.
  • Review of current ancillary testing (neuropsychological, imaging, biomarkers).
  • Discussion of potential for multidisciplinary care and sport retirement guidelines.

Main Results:

  • Overlooking comorbidities can prolong recovery.
  • Multidisciplinary management may shorten patient recovery times.
  • Evidence-based studies on pediatric sport retirement are lacking.

Conclusions:

  • Pediatric concussions require careful clinical diagnosis, considering comorbidities.
  • A multidisciplinary approach is recommended for optimal recovery.
  • Further research is needed on sport retirement decisions in pediatric concussion management.

Related Concept Videos

Traumatic Memory01:20

Traumatic Memory

Emotionally traumatic events often lead to memories that are exceptionally vivid and enduring, sometimes persisting with remarkable clarity throughout an individual's life. A classic example of this phenomenon is a person who survives a car accident. Even years later, they may recall every detail of the event with startling accuracy — the screeching of the tires, the jarring impact, and the acrid smell of burning rubber. Such vividness contrasts sharply with how an individual...
583
Overview of Advanced Functional Groups02:22

Overview of Advanced Functional Groups


Functional groups are groups of atoms with specific chemical properties that occur within organic molecules and are sometimes denoted as “R”. Functional groups can “functionalize” a compound by enabling it to adopt different physical and chemical properties.
Types of Advanced Functional Groups
The table below summarizes some of the major functional groups in organic chemistry.
29.9K
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
262
Extraction: Advanced Methods00:56

Extraction: Advanced Methods

Metal ions can be separated from one another by complexation with organic ligands–the chelating agent– to form uncharged chelates. Here, the chelating agent must contain hydrophobic groups and behave as a weak acid, losing a proton to bind with the metal. Since most organic ligands used in this process are insoluble or undergo oxidation in the aqueous phase, the chelating agent is initially added to the organic phase and extracted into the aqueous phase. The metal-ligand complex is...
1.2K
Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight,...
304
Pharmacokinetics in Pediatric Patients: Drug Metabolism01:24

Pharmacokinetics in Pediatric Patients: Drug Metabolism

In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses...
226