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Bone metabolism in patients with rheumatoid arthritis
1Department of Rheumatology, University Hospital Utrecht, The Netherlands.
Clinical Rheumatology
|March 1, 1988
Abstract:
Bone metabolism in patients with rheumatoid arthritis is reviewed. Two different entities are recognised: 1) a localised periarticular bone loss, due to inflammatory processes and 2) a generalised increased bone turnover, ultimately leading to a loss of axial bone mass. The mechanism of this loss of axial bone is not completely understood; probably immobilisation is the most important factor. The influence of certain drugs is discussed.