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Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as

Margherita Brindisi1, Cristina Ulivieri2, Gloria Alfano1

  • 1European Research Centre for Drug Discovery and Development (NatSynDrugs), University of Siena, Department of Biotechnology, Chemistry and Pharmacy, DoE Department of Excellence 2018-2022, via Aldo Moro 2, I-53100, Siena, Italy; Istituto Toscano Tumori, University of Siena, via Aldo Moro 2, I-53100, Siena, Italy.

European Journal of Medicinal Chemistry
|November 19, 2018
PubMed

Keywords:
Antitumor agentsApoptosisMicrotubule-targeting agentMolecular modelingTubulinX-ray crystallography

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