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Updated: Feb 2, 2026

Analysis of the Ambient Particulate Matter-induced Chromosomal Aberrations Using an In Vitro System
Published on: December 21, 2016
In vitro toxicological activity of particulate matter generated by coal combustion
Hyun-Ki Cho1, Chang-Gyun Park1, Han-Jae Shin2
1College of Agriculture, Life & Environment Sciences, Chungbuk National University, Cheongju 362-763, Republic of Korea.
Abstract:
Herein, the toxicity of particles generated from the complete combustion of 1 g coal at 500, 700, and 900 °C were compared, and combustion at 700 °C generated the most toxins. Chemical analyses revealed that all components except catechol, resorcinol, and aromatic amines were most abundant at 700 °C. Toxicity results confirmed that the relative mutagenicity, cytotoxicity, redox cycling, and production of reactive oxygen species was highest for particles generated at 700 °C. Particles generated during combustion at 700 °C exhibited higher toxicity toward biological systems due to a higher content of toxic compounds.
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