[Optimization of the system of prophylaxis congenital pathology in providing primary health care]

Introduction: reforming primary health care in Ukraine requires the provision of general practitioners - family medicine with prophylactic technologies. Among the last important place is the prevention of the implementation of the risk factors of congenital pathology. This requires thorough study and use of research results to optimize the existing prevention system. The aim: to substantiate and develop an optimized functional and organizational model of the system of the prevention of congenital pathology in the provision of primary care.

Materials and methods: methods of system approach, system analysis, medical-statistical, experimental, graphic modeling are used in the work. Materials: scientific sources on the subject (6 units), normative-legal documents (5 units), forms of state medical statistical reporting (24 units), data of an experimental study conducted in 62 rats in accordance with the requirements of the Helsinki Declaration of 1975, revised in 2000.

Results: it was found that the frequency of thyroid gland diseases that complicated pregnancy, childbirth and postpartum period was 66.99 ± 0.09 per 1000 pregnant women; at the same time, the frequency of diabetes mellitus was 0.99 ± 0.01 per 1000 pregnant women. The cytogenetic effect of the food concentrate of polyphenols of the Enoant grape variety in the experiment with mutagenesis caused by thyroxine has been proved in the experiment. The increased risk of involuntary miscarriage and birth of a child with congenital pathology during the use of pregnant drugs has been confirmed. The limited organizational and preventive technologies in the existing system of the prevention of congenital pathology have been proved. The functional and organizational model of the system of prophylaxis of congenital pathology in the provision of primary care, in which the targeted prophylactic strategies are replaced by the generalized approaches, was substantiated and developed for all components (subject, object of management, block of scientific regulation).

Conclusions: the results of the conducted research are the basis of system optimization of existing technologies for the prevention of congenital pathology, which allows recommending the proposed model for implementation in the conditions of primary medical care in Ukraine.