Related Experiment Video

Updated: Feb 2, 2026

Super-resolution Imaging of Proteus mirabilis Biofilm by Expansion Microscopy
07:10

Super-resolution Imaging of Proteus mirabilis Biofilm by Expansion Microscopy

Published on: July 18, 2025

1.1K

Draft Genome Sequences of Proteus mirabilis K1609 and K670: A Model Strains for Territoriality Examination

Dawid Gmiter1, Grzegorz Czerwonka2, Justyna Malgorzata Drewnowska3

  • 1Department of Microbiology, Jan Kochanowski University, 15 Swietokrzyska Street, 25-406, Kielce, Poland. dawid.gmiter@ujk.edu.pl.

Current Microbiology
|November 19, 2018
PubMed

Insights

Proteus mirabilis bacteria exhibit a hierarchy in territoriality, a novel aspect of their self-recognition (Dienes phenomenon). Genome sequencing of two strains reveals genetic differences potentially explaining this varied territorial behavior.

Area of Science:

  • Microbiology
  • Genomics
  • Bacterial Pathogenesis

Background:

  • Proteus mirabilis is a Gram-negative bacterium known for swarming motility and causing urinary tract infections.
  • The Dienes phenomenon, a form of bacterial self-recognition, is a characteristic of P. mirabilis strains.
  • Previous studies have focused on self-recognition but not on the hierarchical territoriality observed between strains.

Purpose of the Study:

  • To investigate the novel aspect of hierarchical territoriality in Proteus mirabilis self-recognition.
  • To report the draft genome sequences of P. mirabilis strains with distinct territorial behaviors.
  • To identify genetic polymorphisms potentially underlying differences in strain territoriality.

Main Methods:

  • Whole-genome sequencing of P. mirabilis strains K1609 (strong territoriality) and K670 (weak territoriality).
  • Comparative genomic analysis to identify genes related to kin recognition and swarming.
  • Bioinformatic annotation of identified genes and polymorphisms.

Main Results:

  • Draft genome sequences for P. mirabilis K1609 and K670 were generated.
  • Strain K1609 showed closer genomic relation to BB2000 (a model for self-recognition) than K670.
  • Polymorphisms in genes associated with kin recognition and swarming initiation were identified, correlating with observed territoriality differences.

Conclusions:

  • The study presents a novel hierarchy in P. mirabilis strain territoriality, linked to self-recognition.
  • Genomic data suggest specific genetic variations contribute to differential territorial behavior.
  • These strains serve as valuable models for studying bacterial kin recognition and territoriality, offering new research avenues.

More Related Videos

Characterization of a Pathogenic Escherichia coli Strain Derived from Oreochromis spp. Farms Using Whole-Genome Sequencing09:44

Characterization of a Pathogenic Escherichia coli Strain Derived from Oreochromis spp. Farms Using Whole-Genome Sequencing

Published on: December 23, 2022

2.9K
Ultra-long Read Sequencing for Whole Genomic DNA Analysis10:34

Ultra-long Read Sequencing for Whole Genomic DNA Analysis

Published on: March 15, 2019

24.0K

Related Concept Videos

Genomics02:02

Genomics

Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
40.7K
Genomic Imprinting and Inheritance02:30

Genomic Imprinting and Inheritance

Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
37.2K
Per-Unit Sequence Models01:26

Per-Unit Sequence Models

An ideal Y-Y transformer, grounded through neutral impedances, displays per-unit sequence networks akin to those of a single-phase ideal transformer when subjected to balanced positive- or negative-sequence currents. These currents do not produce neutral currents, and their associated voltage drops.
Zero-sequence currents, which are identical in magnitude and phase, generate a neutral current, resulting in voltage drops across the neutral impedance and the low-voltage winding. If the...
450
Genome Size and the Evolution of New Genes03:21

Genome Size and the Evolution of New Genes

While every living organism has a genome of some kind (be it RNA, or DNA), there is considerable variation in the sizes of these blueprints. One major factor that impacts genome size is whether the organism is prokaryotic or eukaryotic. In prokaryotes, the genome contains little to no non-coding sequence, such that genes are tightly clustered in groups or operons sequentially along the chromosome. Conversely, the genes in eukaryotes are punctuated by long stretches of non-coding sequence.
9.1K
Cis-regulatory Sequences02:02

Cis-regulatory Sequences

Cis-regulatory sequences are short fragments of non-coding DNA that are present on the same chromosomes as the genes that they regulate. These fragments serve as binding sites for transcriptional regulators, proteins that are responsible for controlling gene transcription and differential gene expression across cell types in eukaryotes. Cis-regulatory sequences can be close to the gene of interest or thousands of bases away in the DNA sequence; however, those sequences that are further away are...
11.8K
Comparing Mitochondrial, Chloroplast, and Prokaryotic Genomes02:16

Comparing Mitochondrial, Chloroplast, and Prokaryotic Genomes

The present-day mitochondrial and chloroplast genomes have retained some of the characteristics of their ancestral prokaryotes and also have acquired new attributes during their evolution within eukaryotic cells. Like prokaryotic genomes, mitochondrial and chloroplast genomes neither bind with histone-like proteins nor show complex packaging into chromosome-like structures, as observed in eukaryotes. Unlike mitotic cell divisions observed in eukaryotic cells, mitochondria and chloroplasts...
16.1K