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Updated: Feb 2, 2026

Real-time Imaging of Axonal Transport of Quantum Dot-labeled BDNF in Primary Neurons
Published on: September 15, 2014
The BDNF Val66Met Polymorphism Promotes Changes in the Neuronal Integrity and Alters the Time Perception
Victor Marinho1,2,3, Giovanny Rebouças Pinto4,5, Rogério Figueiredo6
1Neuro-innovation Technology & Brain Mapping Laboratory, Federal University of Piauí, Av. São Sebastião n°2819, Nossa Sra. de Fátima, Parnaíba, PI, 64202-020, Brazil. victormarinhophb@hotmail.com.
Abstract:
Studies at the molecular level aim to integrate genetic and neurobiological data to provide an increasingly detailed understanding of phenotypes related to the synchronization ability and brain oscillations in time perception. Genetic variation as a modifying factor at cellular and neurochemical levels permeates several neurofunctional aspects in time-lapse duration concentrating from milliseconds to hours. Thus, the review presents the BDNF Val66Met polymorphism association in a dynamic frame of brain neurotrophic factor expression in the adaptation, integrity, and neuronal synchronism processes in the ability to estimate multisensory stimuli at different time intervals. Our study aims to understand the molecular aspects involved in a neurobiological domain pertinent to the time judgment, tracing a genetic profile of association with psychometric functions and behavioral performances related to timing stimuli.
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