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Actionable Activating Oncogenic ERBB2/HER2 Transmembrane and Juxtamembrane Domain Mutations

Kanika Bajaj Pahuja1, Thong T Nguyen1, Bijay S Jaiswal1

  • 1Molecular Biology Department, Genentech Inc., South San Francisco, CA 94080, USA.

Cancer Cell
|November 20, 2018
PubMed

Keywords:
ERBB2 activationERBB2 structureERBB2/HER2HER2 germline mutationHER2 kinase inhibitorsHER2 somatic mutationanti-HER2 antibodiesjuxtamembrane (JMD) domain mutationtransmembrane domain (TMD) mutation

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