Related Experiment Video

Updated: Feb 2, 2026

Modeling Hepatitis B Virus Infection in Non-Hepatic 293T-NE-3NRs Cells
09:02

Modeling Hepatitis B Virus Infection in Non-Hepatic 293T-NE-3NRs Cells

Published on: June 5, 2020

7.9K

Increased Health and Social Vulnerability Among Hepatitis C Infected Individuals Co-infected with Hepatitis B

Jeffrey K Hom, Danica Kuncio, Caroline C Johnson

    Journal of Health Care for the Poor and Underserved
    |November 20, 2018
    PubMed

    Insights

    Hepatitis B and C infections disproportionately affect vulnerable populations. Over half of hepatitis C and 70% of hepatitis B/C cases were linked to homelessness, incarceration, or mental illness.

    Area of Science:

    • Public Health
    • Infectious Diseases
    • Epidemiology

    Background:

    • Hepatitis B (HBV) and hepatitis C (HCV) infections cause significant illness in the U.S.
    • Populations with histories of incarceration, homelessness, and mental illness are particularly vulnerable.

    Purpose of the Study:

    • To analyze the overlap between viral hepatitis cases and vulnerable populations in Philadelphia.
    • To compare characteristics of hepatitis B/C (HBV/HCV) co-infected individuals with HCV-only cases.

    Main Methods:

    • Utilized data from the Philadelphia Department of Public Health's viral hepatitis registry.
    • Matched registry data with city datasets for shelters, jails, and mental health services.
    • Calculated descriptive statistics for reported cases between 2010 and 2014.

    Main Results:

    • 29,807 HCV cases and 133 HBV/HCV cases were reported from January 2010 to December 2014.
    • 58% of HCV cases and 70% of HBV/HCV cases were linked to at least one vulnerability dataset.
    • HBV/HCV cases showed higher rates of mental health diagnosis, incarceration history, and longer jail stays compared to HCV-only cases.
    • HBV/HCV cases were less likely to be receiving HCV treatment.

    Conclusions:

    • Viral hepatitis, especially HBV/HCV co-infection, is highly prevalent in vulnerable populations.
    • Improved data on HBV/HCV co-infected individuals are crucial for effective health service planning and policy development.

    More Related Videos

    Detection of Low Copy Number Integrated Viral DNA Formed by In Vitro Hepatitis B Infection11:14

    Detection of Low Copy Number Integrated Viral DNA Formed by In Vitro Hepatitis B Infection

    Published on: November 7, 2018

    18.9K
    Intravital Microscopy Imaging of the Liver following Leishmania Infection: An Assessment of Hepatic Hemodynamics10:48

    Intravital Microscopy Imaging of the Liver following Leishmania Infection: An Assessment of Hepatic Hemodynamics

    Published on: July 28, 2015

    13.0K

    Related Concept Videos

    Effect of Hepatic Disease on Pharmacokinetics: Dose Adjustments Due to Hepatic Impairment01:08

    Effect of Hepatic Disease on Pharmacokinetics: Dose Adjustments Due to Hepatic Impairment

    Hepatic impairment, characterized by decreased liver function, does not uniformly mandate adjustments in drug dosage. Whether dosage modifications are necessary depends on various factors related to the drug's metabolism and elimination pathways. If a drug is primarily excreted via the kidneys and bypasses significant hepatic processing, if it undergoes minimal metabolic transformation in the liver, or if it is volatile and primarily expelled through the lungs, dose adjustments may not be...
    280
    Hepatic Portal System01:21

    Hepatic Portal System

    The hepatic portal system, a critical part of our circulatory framework, transports nutrient-laden, deoxygenated blood from the gastrointestinal tract and spleen to the liver. This ingenious system plays an indispensable role in maintaining our body's metabolic equilibrium.
    At its core, the hepatic portal vein is the result of a confluence of the superior and inferior mesenteric veins along with the splenic vein. Each of these veins has a unique role. The superior mesenteric vein is...
    5.9K
    Effect of Hepatic Disease on Pharmacokinetics: Drug Dosing and Hepatic Blood Flow01:26

    Effect of Hepatic Disease on Pharmacokinetics: Drug Dosing and Hepatic Blood Flow

    Chronic liver disease significantly impacts drug metabolism due to alterations in hepatic blood flow and enzyme accessibility. This disruption affects the body's pharmacokinetics—the movement and processing of drugs within the system. Key enzymes crucial for metabolizing medications become less accessible, changing how drugs are processed and utilized. Furthermore, liver disease influences the synthesis of plasma proteins, such as albumin and globulins, which play critical roles in drug...
    244
    Impact of Social Context on Individuals01:21

    Impact of Social Context on Individuals

    Social psychology examines how the real or imagined presence of others influences individuals' thoughts, feelings, and behaviors. A key concept in this field is the role of social context in shaping behavior. The same individual may act differently depending on the social setting, due to the varying expectations and norms associated with each environment. This context-dependent behavior illustrates the influence of social roles, which prescribe appropriate conduct in specific situations.Social...
    332
    Social Psychology and Individual Behavior01:29

    Social Psychology and Individual Behavior

    Social psychology examines how group dynamics, emotions, and cultural influences shape individual actions and decision-making. These elements interact to form behavioral patterns that affect personal choices and social interactions.The Role of Group DynamicsGroups play a crucial role in shaping behavior by reinforcing norms and expectations. Individuals derive a sense of self from group membership, often aligning their behaviors with group norms to maintain social cohesion. For example, an...
    312
    Hepatic Drug Excretion: Influencing Factors01:16

    Hepatic Drug Excretion: Influencing Factors

    The biliary system of the liver, crucial for bile secretion and drug excretion, comprises intrahepatic bile ducts that merge to form the common hepatic duct. This duct, carrying hepatic bile, combines with the cystic duct, draining the gallbladder and forming the common bile duct, which empties into the duodenum. Bile, produced by hepatic cells lining the bile canaliculi, is composed primarily of water, bile salts, pigments, electrolytes, and lesser amounts of cholesterol and fatty acids. Bile...
    581