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[Significance of Endocrine Therapy for Unresected Primary Breast Cancer]
Kanako Kurata1, Masaya Kai, Makoto Kubo
1Dept. of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University.
Gan to Kagaku Ryoho. Cancer & Chemotherapy
|November 20, 2018
Summary
Hormonal therapy offers a safe and effective alternative for patients with unresected breast cancer who cannot undergo surgery. This treatment option showed positive responses in all patients, with no disease progression observed.
Area of Science:
- Oncology
- Endocrinology
Background:
- Surgery is the primary breast cancer treatment, but not suitable for all patients.
- Elderly, high-risk, or unwilling patients may need alternative breast cancer management.
- Hormonal therapy presents a potential optional treatment for unresected breast cancer.
Observation:
- A case series of 8 patients with Stage I-III unresected breast cancer was analyzed.
- Patients received hormonal therapy for an average of 20.1 months.
- Tumor response was evaluated based on complete response, partial response, and stable disease.
Findings:
- Complete response achieved in 4 patients (50%).
- Partial response in 1 patient (12.5%) and stable disease in 3 patients (37.5%).
- No instances of disease progression were recorded during the study period.
Implications:
- Endocrine therapy demonstrates efficacy and safety as an alternative for unresected breast cancer.
- Hormonal therapy expands treatment options for patients unsuitable for surgical intervention.
- Further research into endocrine therapy for unresected breast cancer is warranted.
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