Knomics-Biota - a system for exploratory analysis of human gut microbiota data

Area of Science:

• Microbiology
• Bioinformatics
• Computational Biology

Background:

• Metagenomic surveys of the human microbiome are increasingly prevalent across research, industry, and clinical settings.
• Accessible and intuitive tools for analyzing experimental metagenomic data are in high demand.

Purpose of the Study:

• To introduce Knomics-Biota, a web-based resource designed for the exploratory analysis of human gut metagenomic data.
• To provide researchers with a comprehensive platform for interactive data investigation.

Main Methods:

• Development of a web-service (Knomics-Biota) for metagenomic data analysis.
• Integration of interactive visualizations and statistical analyses.
• Inclusion of publicly available datasets arranged into thematic collections.

Main Results:

• Knomics-Biota enables users to generate and share analytical reports for common experimental designs (e.g., case-control, paired comparison).
• The platform offers interactive visualizations and statistical analyses linked to external factors.
• Analysis is contextualized within thousands of publicly available human gut metagenomic datasets.

Conclusions:

• Knomics-Biota serves as a comprehensive and user-friendly web service for interactive metagenomic data analysis.
• The resource facilitates deeper insights into human gut microbiome research.