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Metabolic and Cardiovascular Comorbidities Among Clinically Stable HIV Patients on Long-Term ARV Therapy in Five

Jose A Hidalgo1,2, Alberto Florez3, Cecilia Agurto4

  • 1Almenara Hospital, Lima, Peru.

The Open AIDS Journal
|November 20, 2018
PubMed

Insights

Stable HIV patients in Peru frequently experience metabolic issues like dyslipidemia, obesity, and diabetes. Management of these non-AIDS defining comorbidities, particularly dyslipidemia, requires improved attention in HIV care policies.

Area of Science:

  • Infectious Diseases
  • Cardiology
  • Endocrinology

Background:

  • Limited data exists on non-AIDS defining comorbidities in stable HIV-infected patients in Peru.
  • Focus on cardiometabolic conditions is crucial for long-term HIV management.

Purpose of the Study:

  • To determine the prevalence of cardiometabolic comorbidities among ambulatory adults receiving antiretroviral therapy (ARV) in Peru.
  • To identify the most frequent metabolic and cardiovascular conditions in this population.

Main Methods:

  • Retrospective review of 305 patient records from Lima-Callao clinics (January-February 2016).
  • Inclusion criteria: adults on ARV for >6 months with no recent AIDS-defining illness.
  • Data collected included demographics, HIV/ARV history, CD4 count, viral load, and diagnosed comorbidities.

Main Results:

  • Dyslipidemia (51.5%) was the most common comorbidity, followed by obesity (11.1%) and diabetes mellitus (7.2%).
  • Hypertension was diagnosed in 8.9% of patients; cardiovascular disease in 3.3%.
  • While most diabetes/hypertension patients received medication, only 29.3% with dyslipidemia did.

Conclusions:

  • A significant burden of metabolic comorbidities exists in stable, ambulatory HIV patients in Peru.
  • Dyslipidemia is highly prevalent but undertreated, necessitating updated HIV care guidelines.
  • Addressing these chronic conditions is vital for optimizing long-term health outcomes in people living with HIV.
Abstract

Keywords:
ARV therapyAmbulatory clinicsCardiovascular comorbiditiesHIV patientsLima-CallaoMetabolic

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