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Updated: Feb 2, 2026

Optimization of the Retinal Vein Occlusion Mouse Model to Limit Variability
Published on: August 6, 2021
Malignant optic glioma masked by suspected optic neuritis and central retinal vein occlusion
Aleksandrs Kalnins1, Mrudula Penta2, Tarek El-Sawy3
1Advocate Christ Medical Center, Integrated Imaging Associates, 4440 W 95th St, Oak Lawn, IL 60453, USA.
Abstract:
Malignant optic glioma presents a clinical and diagnostic challenge, as early imaging findings overlap with other more common causes of optic nerve enhancement and enlargement, potentially leading to delay in diagnosis. This rare diagnosis carries an extremely poor prognosis, with death usually occurring within 1 year. We present a case of malignant optic glioma that was initially diagnosed as optic neuritis and central retinal vein occlusion, and we emphasize the importance of serial imaging and definitive biopsy to promote early diagnosis and treatment of this entity.
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