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Postgenomic Properties of Natural Micronutrients
1V. A. Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia. sharanova.natalia@gmail.com.
Bulletin of Experimental Biology and Medicine
|November 20, 2018
Summary
Natural bioactive compounds can complement toxic cancer therapies, offering milder effects and multiple benefits. Omics-based nutritional biochemistry, including nutrigenetics, is crucial for understanding and preventing chronic diseases.
Area of Science:
- Biochemistry
- Nutritional Science
- Genomics
Background:
- Conventional medicine, including cancer therapy, often relies on toxic drugs with significant side effects.
- Natural bioactive substances offer a potential complementary approach due to their mild cellular action and multitargeted effects.
Purpose of the Study:
- To review the integration of bioactive natural compounds into chronic disease therapy.
- To highlight the role of omics-based nutritional biochemistry in understanding these effects.
- To emphasize the importance of nutrigenetic and nutrimetabolomic analyses.
Main Methods:
- Review of current scientific literature.
- Application of "omics" approaches (genomics, transcriptomics, proteomics, metabolomics) to elucidate biological mechanisms.
- Focus on omics-based nutritional biochemistry.
Main Results:
- Natural compounds can counterbalance the adverse effects of traditional therapies.
- Omics technologies provide insights into the mechanisms of action of bioactive substances.
- Accumulated data support the use of nutrigenetic and nutrimetabolomic analyses.
Conclusions:
- Bioactive natural compounds represent a promising addition to conventional therapies for chronic diseases.
- Omics-based nutritional biochemistry is essential for personalized prevention and treatment strategies.
- Nutrigenetic and nutrimetabolomic analyses are vital for managing chronic disease risk.
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