Related Experiment Video
Updated: Feb 2, 2026

07:54
Accessing the Subdural Space of the Rodent Spinal Cord for Treatment Delivery
Published on: August 8, 2025
506
Lawsonella clevelandensis causing spinal subdural empyema.
A Kumaria1, E K Lucas1, S A Crusz2
1Departments of Paediatric Neurosurgery, Queen's Medical Centre, Nottingham, UK.
British Journal of Neurosurgery
|November 20, 2018
Summary
A rare bacterial infection caused by Lawsonella clevelandensis occurred in a child with a spinal dermoid cyst. This case highlights diagnostic challenges and the need for molecular identification of this fastidious organism.
Area of Science:
- Medical Microbiology
- Infectious Diseases
- Clinical Case Reports
Background:
- Lawsonella clevelandensis is a recently identified bacterium.
- Human infections with this organism are rare, with limited documented cases.
- Understanding its clinical presentation and diagnostic challenges is crucial.
Observation:
- A 2-year-old girl presented with an infected spinal dermoid cyst.
- The infection was caused by Lawsonella clevelandensis, a fastidious organism.
- Diagnosis was complicated by difficulties in culturing the bacterium, necessitating molecular methods.
Findings:
- This report details the seventh worldwide and first UK case of human Lawsonella clevelandensis infection.
- It is the first reported pediatric case and the second spinal infection attributed to this bacterium.
- The case required surgical intervention and prolonged antibiotic treatment.
Implications:
- This case expands the known spectrum of Lawsonella clevelandensis infections.
- It underscores the importance of considering rare pathogens in complex clinical scenarios.
- Highlights the utility of molecular diagnostics for identifying fastidious bacteria.
More Related Videos
Related Concept Videos
Spinal Cord
1.9K
The spinal cord, a critical component of the central nervous system, extends from the base of the brainstem to the lumbar region of the vertebral column. It is essential for maintaining physical stability and facilitating communication between the brain and peripheral parts of the body.
1.9K
The Spinal Cord
31.9K
The spinal cord is the body’s major nerve tract of the central nervous system, communicating afferent sensory information from the periphery to the brain and efferent motor information from the brain to the body. The human spinal cord extends from the hole at the base of the skull, or foramen magnum, to the level of the first or second lumbar vertebra.
31.9K
Spinal Cord: Information Processing
3.6K
The spinal cord is an integral hub for motor and sensory information that enables the brain to communicate with the peripheral nervous system (PNS). This communication consists of relaying sensory data and transmission of motor commands.
Sensory Information Processing
Sensory information processing begins at the sensory receptors located in the skin and other tissues, which detect somatic sensory stimuli such as touch, temperature, or pain. These receptors function as catalysts, initiating...
Sensory Information Processing
Sensory information processing begins at the sensory receptors located in the skin and other tissues, which detect somatic sensory stimuli such as touch, temperature, or pain. These receptors function as catalysts, initiating...
3.6K
Spinal Nerves: Plexus II
2.5K
The plexuses of the lower body include the lumbar, sacral, and coccygeal plexuses, which innervate the abdomen, pelvis, legs, and coccygeal region. These plexuses control the transmission of sensory information and coordinate motor functions of the lower body.
The Lumbar Plexus
The lumbar plexus is situated within the lumbar region of the back and is primarily formed by the first four lumbar spinal nerves (L1 to L4). This plexus extends its branches into several nerves, including the...
The Lumbar Plexus
The lumbar plexus is situated within the lumbar region of the back and is primarily formed by the first four lumbar spinal nerves (L1 to L4). This plexus extends its branches into several nerves, including the...
2.5K
Cranial and Spinal Meninges
4.0K
The cranial and spinal meninges are complex protective structures surrounding the central nervous system (CNS), consisting of the brain and spinal cord. These meninges consist of the dura mater, the arachnoid mater, and the pia mater. They protect the CNS, provide structural support, and aid in circulating cerebrospinal fluid (CSF).
Cranial Meninges
These meningeal layers cover the cranium. The dura mater is the outermost layer of cranial meninges. It is a thick and durable membrane of dense...
Cranial Meninges
These meningeal layers cover the cranium. The dura mater is the outermost layer of cranial meninges. It is a thick and durable membrane of dense...
4.0K
Spinal Nerves: Anatomy
8.8K
Spinal nerves are pivotal conduits in the nervous system, bridging the central nervous system (CNS) with the peripheral nervous system (PNS). These nerves enable a complex communication network between the brain, spinal cord, and the rest of the body, facilitating sensory input, motor output, and autonomic functions.
There are 31 bilateral pairs of spinal nerves, each emerging from the spinal cord through the intervertebral foramina—openings between adjacent vertebrae. These nerves are...
There are 31 bilateral pairs of spinal nerves, each emerging from the spinal cord through the intervertebral foramina—openings between adjacent vertebrae. These nerves are...
8.8K

