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Related Experiment Video

Updated: Feb 2, 2026

Author Spotlight: Insights and Innovations in Gene Expression Manipulation Techniques for Choroid Plexus Research

Author Spotlight: Insights and Innovations in Gene Expression Manipulation Techniques for Choroid Plexus Research

Published on: June 16, 2023

Choroidal biomarkers.

Francesco Pichi¹, Kanika Aggarwal², Piergiorgio Neri³

¹Cleveland Clinic Abu Dhabi, Eye Institute, Abu Dhabi, United Arab Emirates; Cleveland Clinic Lerner College of Medicine, Case Western, Reserve University, Cleveland, OH, USA.

Indian Journal of Ophthalmology

|November 20, 2018

Summary

This summary is machine-generated.

The choroid is crucial for retinal health. Advanced imaging techniques like OCT angiography reveal choroidal blood flow and structure, aiding in diagnosing and monitoring choroidal diseases.

Keywords:

Choriocapillaris choroid enhanced depth imaging optical coherence tomography indocyanine green angiography optical coherence tomography angiography swept-source optical coherence tomography

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An Ex Vivo Choroid Sprouting Assay of Ocular Microvascular Angiogenesis

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Published on: August 6, 2020

Area of Science:

Ophthalmology
Medical Imaging
Retinal Diseases

Background:

The choroid provides essential blood supply to the outer retina.
Choroidal blood flow abnormalities are implicated in various retinal diseases, including AMD and CSR.
Accurate assessment of choroidal structure and function is vital for understanding disease progression.

Purpose of the Study:

To review imaging findings of choroidal diseases.
To highlight biomarkers for disease activity and treatment response.
To discuss advancements in choroidal imaging technologies.

Main Methods:

Indocyanine green angiography for visualizing choroidal veins.
Enhanced depth imaging (EDI) and swept-source optical coherence tomography (SS-OCT) for structural analysis.
OCT angiography for dye-free evaluation of choroidal blood flow.

Main Results:

Long-wavelength SS-OCT allows deep imaging of the choroid and choroid-sclera interface.
Quantification of choroidal thickness and visualization of large choroidal vessels are possible with SS-OCT.
OCT angiography provides detailed assessment of choriocapillaris and choroidal vasculature.

Conclusions:

Advanced imaging modalities have significantly improved the analysis of choroidal structure and function.
Imaging findings serve as crucial biomarkers for diagnosing and managing choroidal diseases.
These technologies enable precise monitoring of treatment efficacy in various chorioretinal conditions.