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A simple lateral flow biosensor for rapid detection of lead(ii) ions based on G-quadruplex structure-switching
Dou Wang1, Chenchen Ge, Kongpeng Lv
1Department of Hepatobiliary and Pancreatic Surgery, The 2nd Clinical medicine College (Shenzhen People's Hospital) of Jinan University, Shenzhen 518020, China. baomi94@163.com.
Abstract:
A novel lateral flow biosensor for rapid detection of Pb2+ was established for the first time based on Pb2+-induced G-quadruplex structure-switching. Semi-quantitative results could be read by reference to a colorimetric card. The whole process only took 15 minutes with a visual detection limit of 25 nM.
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