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The Relationship Between the Sighting Eye and Functional and Structural Asymmetries in Glaucoma
Jin A Choi1, Il-Young Jung1, Donghyun Jee1
1Department of Ophthalmology and Visual Science, St. Vincent's Hospital, College of Medicine, the Catholic University of Korea, Seoul, Korea.
Patients with open-angle glaucoma predominantly choose their better-seeing eye. Functional vision loss is more pronounced in the non-sighting eye, indicating asymmetry in glaucoma progression.
Area of Science:
- Ophthalmology
- Neuroscience
Background:
- Open-angle glaucoma (OAG) is a leading cause of irreversible blindness.
- Understanding factors influencing disease progression and patient experience is crucial.
Purpose of the Study:
- To investigate the relationship between the preferred sighting eye and functional/structural asymmetries in patients with OAG.
Main Methods:
- 200 patients with bilateral OAG underwent dominant eye testing.
- Eyes were classified as 'better' or 'worse' based on visual field (VF) mean deviation (MD).
- Patients were grouped based on whether their sighting eye corresponded to the better or worse eye.
Main Results:
- The sighting eye predominantly corresponded to the eye with better VFs.
- Worse eyes in the preferred sighting eye group showed significantly lower MD and larger intereye MD differences.
- Functional deterioration was more evident in non-sighting eyes.
Conclusions:
- Sighting eye choice is linked to functional asymmetry in OAG.
- Non-sighting eyes exhibit more significant functional deterioration.
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