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Updated: Feb 2, 2026

The Influence of Liver Resection on Intrahepatic Tumor Growth
Published on: April 9, 2016
Perivascular epithelioid cell tumor outgrowth from the liver
Mahir Kirnap1, Gonca Ozgun2, Gokhan Moray1
1Departments of Transplantation, Baskent University, Ankara, Turkey.
Introduction:
Perivascular epithelioid celltumor (PEComa) is a rare mesenchymal neoplasia and can be found in various body sites. On the other hand, hepatic PEComa is very rare, with only a few studies having reported hepatic malignant PEComa. There is no gold standard regarding the use of diagnostic imaging studies. The diagnosis of hepatic PEComa is made by a positive immunohistochemical staining for HMB45 and Melan A. Herein, we discussed the therapeutic and follow-up process of a symptomatic hepatic PEComa case.
Presentation Of Case:
A 22-year-old woman presented with a palpable mass in abdomen. A computerized tomographic examination showed a giant hepatic mass of left lobe origin, which was excised surgically. The pathology result was reported as a PEComa.
Discussion:
The diagnostic approach, treatment modalities, and follow-up procedures are not standard. The main treatment modality for PEComa is surgical excision with adequate surgical margin.
Conclusion:
A longer follow-up is required for patients with hepatic PEComa because the nature of the disease is not entirely clear.
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