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Construction and Characterization of a Novel Vocal Fold Bioreactor
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Construction and Characterization of a Novel Vocal Fold Bioreactor

Published on: August 1, 2014

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[Clinical evaluation of vocal fold paralysis in 207 children]

B Duan1, Y H Ni1, Y Q Dai1

  • 1Department of Otorhinolaryngology Head and Neck Surgery, Children's Hospital of Fudan University, Shanghai 201102, China.

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi = Chinese Journal of Otorhinolaryngology Head and Neck Surgery
|November 20, 2018
PubMed

Insights

Pediatric vocal fold paralysis has varied causes. Left-sided paralysis often stems from cardiovascular issues, while bilateral cases are linked to congenital malformations, with both showing poor prognosis.

Area of Science:

  • Pediatric Otolaryngology
  • Pediatric Pulmonology
  • Pediatric Cardiology

Background:

  • Vocal fold paralysis (VFP) in children presents unique diagnostic and management challenges.
  • Understanding the specific etiologies and clinical features is crucial for effective patient care.

Purpose of the Study:

  • To investigate the causes and clinical characteristics of VFP in pediatric patients.
  • To offer insights for improved diagnosis, treatment, and prognosis.

Main Methods:

  • Retrospective analysis of 207 children diagnosed with VFP.
  • Inclusion of follow-up data to assess outcomes.

Main Results:

  • Left-sided VFP (151 cases) primarily caused by pulmonary arterial hypertension.
  • Bilateral VFP (43 cases) associated with respiratory issues and congenital tracheoesophageal malformations.
  • Right-sided VFP (13 cases) linked to intracranial lesions (8 cases) or idiopathic (2 cases).

Conclusions:

  • Cardiovascular diseases are the leading cause of left-sided VFP.
  • Congenital tracheoesophageal malformations are the primary etiology for bilateral VFP.
  • Neoplastic and central nervous system lesions are key causes of right-sided VFP, with poor prognosis for bilateral and right-sided VFP.

Keywords:
ChildrenEtiologyPrognosisVocal fold paralysis

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