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Updated: Feb 2, 2026

Synthesis of Indoxyl-glycosides for Detection of Glycosidase Activities
Published on: May 27, 2015
Two new xanthone glycosides from Swertia punicea Hemsl. and their anti-inflammatory activity
Lin-Yun Mou1,2, Hai-Yan Wu2, En-Guang Ma2
1Technology Center, China Tobacco Yunnan Industrial Co., Ltd, Kunming, P. R. China.
Abstract:
Two new xanthone glycosides (1-2), together with seven known analogues (3-9), were isolated from whole herb of Swertia punicea. The structures of these metabolites were established on the basis of detailed spectroscopic analysis and comparison with data reported in the literature. In an in vitro test, all isolates were evaluated for their anti-inflammatory activity. The results revealed that all of them showed significant anti-inflammatory activity with IC50 values ranging from 1.237 to 3.319 mM. Compounds 3, 4, and 5 (IC50 values in the range 1.237-1.987 mM) displayed more potent anti-inflammatory activity than the positive control, indomethacin (IC50 value of 2.004 mM).
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